In My Cute Roommate 2, the big day has finally arrived, and the protagonist is graduating from high school. Now he's going to enter adulthood and go off to college. He'll move in with his big fat ugly bully cousin, whom he hasn't seen since childhood. He moved into a big city, and the lifestyle here is nothing like what he's used to. So it isn't long before he takes up the opportunity to dive headfirst into all the debauchery a college student can enjoy.